The Wuxi section of the Grand Canal of China originated during the Shang and Zhou dynasties, took shape in the Spring and Autumn Periods, developed further during the Sui and Tang dynasties, and prospered in the Ming and Qing Dynasties. To this day, it continues to serve essential functions such as transportation, flood control, drainage, cultural tourism, and ecological corridor, playing a pivotal role in various aspects of Wuxi’s economic and social development, as well as people’s production and livelihood. From the viewpoint that Wuxi is a witness to the evolution of the Grand Canal and a pioneer in the preservation, inheritance, and utilization of the Grand Canal, the author discusses Wuxi’s contributions to the conservation and utilization of the Grand Canal of China and Wuxi’s exploration into sustainable utilization of the Grand Canal. This book serves as a reference for researchers in fields such as history, culture, economy, tourism, water resources, transportation, ecology, and urban studies, as well as teachers and students of related majors.