Cell Biology is the most taught basic science course in medical school as it is one of the most rapidly
developing subjects in science. Cell biology overlaps with molecular biology, histology, pathology, cancer
biology, neuroscience, and many other major related disciplines. Having an up-to-date Cell Biology
textbook that covers many functional aspects is essential for medical students to ¡°cross the bridge¡±
between basic sciences and clinical courses.
This textbook was edited and modified from Medical Cell Biology, Steven R. Goodman ed., Elsevier,
2008. The first several chapters serve as comprehensive introductions into organelle structure, functions
and gene expression. The second half of this book details many topics in medical science, including cell
signaling pathways, cell cycle, programmed cell death, and cancer. New technologies such as atomic force microscopy, proteomics, and gene therapy are also covered.
Unlike many other general-purpose Cell Biology textbooks, this one is more medically oriented.We decided to keep all chapters in this edited version from the original book. In our edit, however, weremoved some graduate level material, as it would be either too sophisticated, or covered by other courses(histology, pathology, etc.). Students in China generally take Cell Biology in their freshmen year, so wewould like to give students a thoroughunderstanding of basic concepts.We felt that it was proper to also add several important topics. Much progress has been made in ourfield. Advances in single-cell technologies, induced pluripotent stem cells (iPSC), epigenetic modifications,and revelations in next generation sequencing make it almost impossible to cover everything necessarywithout restructuring.We realized that a concise, tailor-made version of a widely used textbook can be an excellent toolfor medical students. However, creating such a resource required hard work and dedication from manyfaculty members. Most of the editors have been teaching cell biology for more than 10 years, and manyhave doctoral degrees on cell biology or related subjects.I hope this book will give you just a snapshot of the ever-changing world of life sciences. Best of luckand we hope you find your journey into cell biology filled with fascination and exhilaration.
LI Guang
Professor and Chairwoman
Department of Genetics
College of Basic Medical Sciences
Tianjin Medical University
July 22, 2018
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